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Director, Radioligand Therapy at Calyx

Calyx · Needham, United States Of America · Onsite

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What can we offer you?

Apart from job satisfaction, we can offer you:

HEALTH

  • Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)

YOURSELF

  • Paid time off policy including holidays and sick time

  • Internal growth and development programs & trainings

WEALTH

  • 401(k) program, life & accident insurance and disability insurance

Job Purpose

Provide senior level scientific, business and strategic leadership for diverse sponsor- driven preclinical oncology discovery programs from idea inception through to candidate nomination and early clinical development.

Key Responsibilities

  • Responsible for scientific output and program leadership at Scientific Lead level; accountable for managing technical and operational excellence, in delivering sponsor-driven programs
  • Serve as an oncology disease area leader and/or Radiopharmaceutical and/ or ADC discovery and development and/or Imaging subject matter expert providing advisory role with the clients.
  • Innovate and drive scientific and process strategy for local preclinical sites and/or global sites in partnership with Discovery preclinical services leaders.
  • Enforce scientific rigor and high quality and timely execution of partnered and internal R&D programs, while enhancing process efficiencies.
  • Strategic planning and leading innovative capability initiatives to expand scientific capabilities and offerings, including tumor models (e.g. PDX, tumor resistance, orthotopic), multimodal Imaging technologies and molecular techniques.
  • Engage clients directly and in association with BD teams, in acquiring new clients and business opportunities to drive growth and profitability.
  • Manage and scale business responsibly, with a balanced approach of prioritizing client satisfaction and operational efficiency to improve credibility.
  • Interact with study directors and sponsors and provide scientific oversight of study design, preparation of protocols, high quality delivery, interpretation of data, and preparation of reports.
  • Mentor a team of study directors and juniors-functional scientists either directly or work collaboratively in a matrixed environment.
  • Represent Perceptive at scientific meetings and support sales and marketing teams; Externalize science and innovation by authoring posters and publications.
  • Work with the Delivery team in authoring and/or reviewing technical documents, study and IACUC protocols, interim and final reports, presentations etc.
  • Identify key science-based challenges and determine resolution of issues and advance scientific programs through exemplary leadership

Functional Competencies (Technical knowledge/Skills)

  • Hands-on experience either with radiochemistry or acquiring pre-clinical imaging data, familiarity with data acquisition, analysis techniques, quality control, and experience in interpretation and presentation of such data
  • Deep and/or broad experience applying imaging to the study of disease in one or more therapeutic areas
  • Experience with relevant in vitro/ex vivo/ in vivo methodologies including Flowcytometry, Multimodal Imaging, Tumor modeling, Radioligand binding, Autoradiography, and Immunohistochemistry
  • Expertise in small molecules or biologics radiochemistry and/ or ADCs
  • Expertise in the design, execution, analysis, and interpretation of pharmacology, Dosimetry, and/or efficacy studies in rodent models
  • Excellent interpersonal, verbal and written communication skills.
  • A flexible attitude with respect to work assignments and new learning.
  • Ability to manage multiple and varied tasks with enthusiasm and prioritize workload with attention to detail.
  • Ability to coach others to succeed in enhancing individual and professional development.  Sharing knowledge, skills, and expertise with others. 
  • Financial management and acumen, with an ability to strictly manage a complex and large budget to a demanding target. 
  • Builds and maintains an in-depth knowledge of technology within the oncology disease area and how it affects customers adopting our products.
  • Maintains an up-to-date awareness of trends, tools, technology, techniques and processes that affect testing and technology within the Life sciences domain.

Experience, Education, and Certifications

  • Education: Ph.D. in Pharmacology, Cancer Biology, Molecular biology, Radiochemistry, or related discipline is preferred. Post-doctoral experience in a related discipline is a plus.
  • An equivalent combination of education and experience with documentation as a subject matter expert in the discipline of Oncology/ Radioligand therapies/ Imaging may be accepted as a satisfactory substitute for the requirements listed above.
  • Experience: Minimum of 6-10 years related experience in research or pharmaceutical environment. Management experience is essential.
  • Other: Experience in use of desktop applications (word processing, spreadsheets, databases) and network navigation required.
  • Proven line management and leadership management.
  • Experience using tools to communicate progress to Stakeholders.
  • English: Fluent.

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