We have a vacancy for a Senior Scientist to join the Bioassay team at our Cambridge (UK) site. In this primarily lab-based role you will be working as part of the immunology group on client-facing projects, and will have the opportunity to learn new techniques in a fast-paced but supportive environment.
Candidates will be expected to demonstrate deep knowledge of immunology with an emphasis on in vitro PBMC-based assays. Significant experience in bioassays, especially using PBMCs and multi-colour flow cytometry to evaluate a range of immune subsets is essential.
Abzena provides the most complete set of solutions in integrated early discovery to mid-phase biotherapeutic and ADC drug development services in the pharmaceutical industry. Working with companies and academic groups all over the world, Abzena supports the development and manufacture of better treatments for patients. Multiple antibodies which have been created using Abzena’s technologies are currently being progressed through clinical development by our partners.
Situated on an attractive parkland estate, in a spacious, beautifully landscaped setting, the Abzena building on the Babraham Research Campus, Cambridge has been purpose-built to accommodate Abzena’s needs and enables all the Group’s UK-based science teams to work together in a single, state-of-the-art facility.
Responsibilities
Responsible for day to day management of studies
Responsible for delivery of key/discrete work packages
Design, co-ordinate and perform multiple experiments
Independently undertake advanced research, performing complex science without supervision
Investigate new techniques under direction
Prepare data for external presentations and reports
Contribute to writing and reviewing reports
Contribute to the preparation of posters and conference presentations
Attend and contribute to internal meetings
Analyse and interpret own data
Review data from junior staff
Contribute to writing and reviewing Quality and Controlled documents
Undertake any other duties relevant to the position and level
Manage own and if necessary others’ work schedule
Line manage junior staff, if appropriate
Supervise, coach and mentor junior staff and help to develop their technical skills
Review new technologies to support customer projects and make recommendation
Qualifications
BSc or MSc with a minimum of 4 years relevant R&D experience in immunology or a related field.
Relevant laboratory experience, such as isolating, maintaining and passaging both primary cells and cell lines, and setting up biochemical (e.g. ELISA) and cell-based assays (e.g. proliferation, cytotoxicity, internalization, signalling, immunophenotyping, cytokine release) using fluorescence or luminescence plate-based methods, flow cytometry or fluorescence microscopy.
Extensive flow cytometry experience and confidence in designing and analysing multi-colour panels is essential. Familiarity with FlowJo software is desirable.
Demonstrated skills in assay design, troubleshooting and data analysis.
Be proactive and independent with good communication skills and high level of attention to detail.
Be a committed team player able to work well within small teams or individually as well as contribute to the wider group.
UK EEO: Abzena is committed to promoting equal opportunities in employment. All our employees and any job applicants will receive equal treatment regardless of age, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief, sex or sexual orientation (“Protected Characteristics”).
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