Hybrid Senior Scientist, Parallel Medicinal Chemistry - Discovery Chemistry at Janssen Research & Development, L.L.C.

Janssen Research & Development, L.L.C., a division ofJohnson & Johnson's Family of Companies is recruiting for a SeniorScientist, Parallel Medicinal Chemistryin Discovery Chemistry, for our site in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what mattersmost is helping people live full and healthy lives. We focus on treating,curing and preventing some of the most devastating and complex diseases of ourtime. And we pursue the most promising science, wherever it might befound. 

Janssen Research & Development, LLC discovers and develops innovativemedical solutions to address important unmet medical needs in oncology,immunology, neuroscience, infectious diseases and vaccines, and cardiovascularand metabolic diseases. Please visit http://www.janssenrnd.com/ for moreinformation. 

We are Janssen. Our mission drives us. Our patients inspire us. We collaboratewith the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of ouremployees and committed to inclusion. Proud to be an equal opportunityemployer.

The newly formed Discovery Chemistry group is committed to the delivery of highquality drug candidates working with all six Janssen Therapeutic Areas (TAs).This mission requires deep scientific expertise in a number of disciplinesincluding chemistry, cellular and molecular pharmacology, enzymology, andscreening technologies coupled with an ability to work collaboratively withinternal and external partners. Building on a strong legacy of success, we arecurrently seeking an outstanding individual to join our team as SeniorScientist, Parallel Medicinal Chemistry, Discovery Chemistry. This positionwill be based at our drug discovery site in Spring House, PA.

We are seeking an experienced medicinal chemist with parallel synthesisexpertise to advance small molecule drug discovery programs toward the clinic.In this laboratory-based position, the successful candidate will partner withboth internal and external medicinal chemistry teams to generate innovativesolutions to synthetic and medicinal chemistry challenges within the context ofsmall molecule drug discovery projects. She/he will maintain close interactionswith computer assisted design scientists, biologists, pharmacologists, andpharmaceutical development scientists. Strong people skills and the ability tothrive in a team and goal driven environment are key attributes. 

This individual must also excel in communication and have strong interpersonalskills necessary to influence in a collaborative multidisciplinaryenvironment. 

Responsibilities of the Senior Scientist include: 

• Maintaining a high level of productivity in thelaboratory setting.
• Lead collaborations with medicinal chemistry teams,computational chemists and therapeutic area biologists to apply automatedchemistry capabilities, such as parallel medicinal chemistry, modern catalysisscreen, High throughput Experimentation (HTE) and High Throughput Purification(HTP) to accelerate Discovery programs
• Supervise and direct automated chemistry and medicinal chemistry activities internally and/or at contract research organizations (CROs)
• Analyze screening data, perform literature reviews, design, propose, and execute medicinal chemistry plans, coordinate chemistry and biology data to support compound progression and patent strategies
• Serve as a scientific expert in parallel medicinal chemistry with both internal and external partners and provide recommendations regarding new targets, new synthetic strategies and emerging external chemistry capabilities.
• Ensure optimal interaction/communication and provide updates on project status to Discovery leadership
• Drafting, executing and serving as lead authoron research published in peer reviewed journals, and presenting work atscientific conferences.

%3Cfont size=%223%22 face=%22Arial%22%3E%3Cul type=%22disc%22%3E%3Cli%3EPhD in synthetic organic or medicinal chemistry is required%3C/li%3E%3Cli%3EPostdoctoral experience is preferred%26nbsp;%3C/li%3E%3Cli%3EAt least 3 or more years of experience at a pharmaceutical industry in medicinal chemistry Is required.%3C/li%3E%3Cli%3EIn-depth knowledge and extensive experience in parallel medicinal chemistry and/or high throughput experimentation (HTE) is required. %3C/li%3E%3Cli%3EStrong track record of achievement in the synthesis of complex molecules and/or synthetic methodology development, with deep knowledge of modern synthetic %26amp; analytical techniques is required.%3C/li%3E%3Cli%3EProven track record of scientific contributions including peer reviewed publications, patents and presentations is required.%3C/li%3E%3Cli%3EExperience with computational chemistry methods and biophysical techniques such as X-ray crystallography is preferred.%3C/li%3E%3Cli%3EIndependent thinking and the ability to effectively collaborate in a highly matrixed environment is required.%3C/li%3E%3Cli%3EExcellent oral and written communication skills, including preparation of presentations is required.%3C/li%3E%3Cli%3EUp to 5% travel is required.%3Cbr%3E %3Cbr%3E Johnson %26amp; Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.%3C/li%3E%3C/ul%3E%3C/font%3E Apply Now