Senior Validation Engineer bei Serán BioScience

Duties and Responsibilities

• Leads the commissioning and qualification (C&Q) of new and existing equipment and systems for OSD manufacturing, facilities, and utilities, ensuring compliance with cGMP, FDA, and EU regulatory standards
• Supports the clinical technology transfer and operations in design, scale-up, optimization, and troubleshooting of OSD processes and equipment
• Develops and executes protocols for equipment IQ/OQ/PQ in alignment with site validation master plans and project timelines
• Collaborates with cross-functional teams to define equipment specifications, user requirements (URS), and establish project timelines and budgets
• Manages installation activities, equipment FAT/SAT execution, and vendor coordination to ensure technical and compliance requirements are met
• Collaborates with multidisciplinary team to complete change controls, deviations investigations, and CAPAs as required
• Supports regulatory inspections and client audits
• Performs other related duties as assigned
• Responsibilities may increase in scope to align with company initiatives

Required Skills and Abilities

• Demonstrates knowledge of cGMPs guidelines and regulations acquired through education, experience, and training
• Preference for those who posses knowledge of Global Regulatory requirements (E.g., FDA / MHRA / EMEA)
• Showcases foundational understanding of the compliance and technical requirements for the application of various scientific concepts used in developing different dosage forms of pharmaceutical products (primarily oral solid dose, while experience with sterile products is desired)
• Experience with regulatory expectations and industry practices for CQ and Validation using Product Lifecycle approach
• Experience with designing CQV plans for Facilities, Utilities, and Process equipment desired
• Ability to manage multiple projects, create and work within internal timeliness, solve problems, deliver on commitments, and utilize interpersonal skills in a cross-functional team
• Strong time-management skills and the ability to organize and coordinate multiple projects at once
• Communicates effectively and maintains productive relationships with coworkers, clients, and other contacts outside the Company
• Ability to prioritize tasks and to keep leadership apprised of performance timelines
• Accepts feedback from a variety of sources and constructively manages conflict
• Demonstrates leadership skills with ability to motivate and coach cross functional teams
• Experience in FAT/SAT of process equipment, and knowledge operating principles of typical OSD process equipment preferred.
• Proficiency in enterprise systems, Microsoft Office, and other office productivity tools, with aptitude to learn new software and systems

Education and Experience

• Bachelor's degree in relevant technical field
• Requires a minimum of 8 years of quality, validation, or engineering experience in non-sterile clinical and commercial pharmaceutical manufacturing
• Fundamental understanding of process equipment, utilities, manufacturing process, cleaning process and Quality systems used in the pharmaceutical/biotech industry
• 8 years of GMP compliance experience, including knowledge of 21 CFR Part 11 requirements, GAMP 5, among others

Physical Requirements

• Prolonged periods of sitting or standing at a desk and working on a computer
• Prolonged periods of sitting or standing in a manufacturing environment
• Must be able to lift fifteen pounds at times
• Adheres to consistent and predictable in-person attendance