Sr. Director, Marketing at Lexeotx

The Senior Director of Marketing & Market Development will play an integral role in bringing our groundbreaking AAV gene therapies to patients with genetic cardiomyopathies. In this high-impact role, the incumbent will build Lexeo’s marketing function from the ground up, shaping brand strategy, market development, and launch readiness for first-in-class therapies poised to transform care in cardiac genetic diseases with high unmet need. You’ll combine strategic vision with hands-on execution, crafting compelling scientific narratives, driving disease awareness, and preparing providers, patients, and payers for a new era in gene therapy. This is a rare opportunity to define how life-changing science becomes real-world medicine. 

Primary Responsibilities

Build, lead, and scale the marketing function; manage budget, resources, vendor/agency relationships, and KPIs tied to demand generation and launch readiness 

Develop and execute integrated brand and marketing strategies for Lexeo’s cardiac pipeline(initially US-focused and future global expansion) 

Shape and evolve Lexeo’s brand story as a leader in genetic cardiovascular medicine, partner with external communications (media, PR, social, thought leadership, IR) 

Build deep customer segmentation and personas across key stakeholders: opinion leaders, cardiologists, genetic specialists, patient advocacy groups, and other members of multi-disciplinary care teams 

Lead disease awareness and diagnosis-activation initiatives in partnership with Medical and Patient Affairs 

Define evidence needs and value propositions for payer engagement, pricing, and provider strategies 

Contribute to strategic planning and commercial prioritization across the portfolio 

Develop messaging frameworks for HCPs, patients, and payers, emphasizing genetic causes, durability, and impact of therapies. 

Expand Lexeo commercial infrastructure with an eye towards commercial launches, including data and analytics, field reporting, patient support and commercial intelligence 

Serve as the commercial voice on cross-functional teams, ensuring alignment from early stage through launch 

Collaborate with new and growing field teams, including market access, medical affairs, field reimbursement and sales 

Required Skills & Qualifications

Bachelor’s in Life Sciences, Marketing, or Business required; MBA, PharmD, or PhD preferred. 

10+ years in life sciences marketing (rare disease, gene therapy, advanced biologics), with both upstream (strategy, portfolio) and downstream (brand, digital) experience. 

Experience in developing launch readiness for novel therapies (cell/gene therapies, biologics in rare/monogenic disease); experience in specialty/high-science areas is preferred 

Strong scientific acumen; familiarity with AAV platforms, manufacturing, and regulatory pathways. 

Deep competency in digital/omnichannel marketing: CRM, automation, SEO/SEM, analytics, content strategy. 

Strong cross-functional collaboration skills and ability to influence senior leadership 

Ability to translate complex science into compelling commercial narratives 

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