Synthego is enabling genome engineering at scale with a blend of scientific instrumentation, industrial automation, and data science. Our team of scientists and engineers are putting multidisciplinary fields together to solve problems that no one field can tackle alone.
We are searching for a motivated and enthusiastic individual to join our Chemistry Development team to improve our oligonucleotide manufacturing process. As a Research Associate at Synthego, you will join our growing Chemistry Development team and have direct responsibility for the synthesis and purification of RNA at several scales. With a focus on the successful introduction and adoption of new technologies in operations, this role will collaborate closely with the hardware, software, operations, and quality teams.
Rate offered will be based on experience and location.
What You'll Do:
Synthesize, purify and analyze oligonucleotides to specifications, using proprietary and commercial instrumentation.
Analyze data from assays such as UV, chromatograms and mass spectrometry for optimizing experimental conditions and determining root causes of failures
Work with Process Chemists, Development Engineers, and Research Scientists to execute developmental processes and collaborate on designed experiments
Conduct experimentation using automated instrumentation and liquid handling equipment
Practice continuous improvement by contributing ideas and suggestions to new and existing processes
Generate and maintain records or documents in a detailed and consistent manner
Assist with Quality data management, including writing new or updating SOP’s
Present findings alongside colleagues to an interdepartmental team
About You:
BS in Chemistry, Chemical Engineering, Bio-engineering or a similar field
1-3 years of industry experience within a research/manufacturing/production environment, preferably in a small company/start-up setting
Proficiency in data analysis with languages such as Python, SQL.
Understanding of aseptic handling techniques, including liquid handling, pipetting, reagent preparation, and consumables.
Experience using larger scale instrumentation such as HPLC’s, synthesizers, buffer exchangers, and/or liquid handlers.
Strong desire to work in a fast-paced, collaborative start-up environment
Demonstrates strong interpersonal and communication skills (both written and oral)
Demonstrates ability to work independently and as part of a team to curate and execute development projects.
Nice to Haves:
Knowledge of oligonucleotide chemistry or reagent manufacturing
Familiar with biotechnical instrumentation in aspects such as coding new methods, data analysis pipeline, servicing, etc
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