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Research Scientist, Osteosarcoma, Levi Lab bei UT Southwestern Medical Center

UT Southwestern Medical Center · Dallas, Vereinigte Staaten Von Amerika · Onsite

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%3Cp style=%22font-family: Arial;%22%3E%3Cb%3EWHY UT SOUTHWESTERN?%3C/b%3E%3Cbr%3EWith over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to %3Ca href=%22https://www.utsouthwestern.edu/newsroom/articles/year-2022/july-us-news-best-hospital.html%22 target=%22_blank%22 rel=%22noopener%22%3EU.S. News %26amp; World Report%3C/a%3E, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you%27ll discover a culture of teamwork, professionalism, and a rewarding career! %3Cbr%3E%3Cbr%3E%3Cb%3EJOB SUMMARY%3C/b%3E%3Cbr%3EPlans, coordinates, directs, and participates in work of smaller research project or major unit of large research project in field of specialization for which incumbent is particularly qualified in terms of extensive training and/or experience.%3C/p%3E%0A%3Cp style=%22font-family: Arial;%22%3EThe Levi laboratory in the Division of Burn, Trauma, Acute and Critical Care Surgery in the Department of Surgery has an opening for a Research Scientist. The Levi lab%26rsquo;s mission is to improve the lives of people living with skin and musculoskeletal injuries and diseases through rigorous science and compassion. Current projects in the Levi laboratory are related to the molecular biology behind tissue fibrosis and the repair and regeneration process in tendon, muscle, and bone. The laboratory integrates multiomics-based approaches with investigations of musculoskeletal development, homeostasis, repair, and regeneration. The laboratory uses transgenic animal models combined with bioinformatic approaches to understand the cell-cell interactions that occur within the stem cell niche under physiological conditions and strives to understand how these divergent signaling mechanisms may guide future therapeutic strategies to promote faithful repair of damaged tissue.%3C/p%3E%0A%3Cp style=%22font-family: Arial;%22%3EThe Levi Lab is looking for a Research Scientist with an Osteosarcoma focus to join the team who is willing to commit to at least two years. The Research Scientist will support ongoing bench and animal work within the lab related to tendon injury/fibrosis, muscle injury/fibrosis or bone/tendon/muscle regeneration. Duties will include routine molecular bench work combined with the use of animal models (animal handling, injections, surgeries, sample collection) as well as downstream processing (histology, immunofluorescent stain and confocal imaging, flow cytometry, cell culture, single cell and bulk RNA sequencing) under supervision of the PI.%3C/p%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cstrong%3ELaboratory Expectations%3C/strong%3E%3C/p%3E%0A%3Cul%3E%0A%3Cli style=%22font-family: Arial;%22%3ERoutine molecular bench work combined with the use of animal models%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EAnimal handling, injections, modified diet maintenance, surgeries, and sample collection%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EDownstream processing%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EHistology, immunofluorescent stain and confocal imaging, flow cytometry, and work with cell cultures and single-cell and bulk RNA sequencing%3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cstrong%3EPreferred Experience%3C/strong%3E%3C/p%3E%0A%3Cul%3E%0A%3Cli style=%22font-family: Arial;%22%3EAble to utilize a variety of molecular biology techniques, including but not limited to PCR, qPCR, western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9 gene editing, and next generation sequencing.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EExperience with animal handling, animal breeding, genotyping, and animal surgery.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EExperience with single-cell transcriptomic analyses.%26nbsp; %26nbsp; %26nbsp;%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EExperience with histology pipeline from tissue harvest to embedding, sectioning, staining, and confocal microscopy.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EExperience with flow cytometry and mass spectrometry.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3E%26nbsp;Excellent written and oral communication and organizational skills.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3E%26nbsp;Able to perform data analysis and interpretation using bioinformatics tools, statistical methods, and relevant software packages.%3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cstrong%3ELaboratory Duties%3C/strong%3E%3C/p%3E%0A%3Cul%3E%0A%3Cli style=%22font-family: Arial;%22%3EAnimal breeding, genotyping, handling, and surgery%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EMolecular biology techniques, including but not limited to PCR, qPCR, western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9 gene editing, and next generation sequencing.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EFlow cytometry and mass spectrometry.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EHistology pipeline from tissue harvest to embedding, sectioning, staining, and confocal microscopy.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EDesign and execute experiments to investigate molecular mechanisms underlying biological processes.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EPlan and develop standard operating protocols for experimental protocols.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EReview and analyze resulting research data.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3ERevise techniques or approaches to work problems that are indicated as necessary by research data.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EMay confer with industrial, governmental, or other groups concerning progress or results of research project.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EMaintain a respectful and inclusive laboratory environment.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EMaintain a clean and functional workspace.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EAnalyze and interpret experimental data using relevant software and statistical methods.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EStay current with advances in molecular biology research and contribute to the development of new methodologies and techniques.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EPrepare research findings for publication in scientific journals and present results at conferences and meetings, including weekly laboratory meetings and reading/writing clubs.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EContribute to grant writing and fundraising efforts to support research activities.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3ECollaborate with interdisciplinary teams to contribute molecular biology expertise to research projects and initiatives.%3C/li%3E%0A%3Cli style=%22font-family: Arial;%22%3EAssist in the training and supervision of junior laboratory personnel, including technicians, graduate students, and postdoctoral fellows.%26nbsp;%3Cbr%3E%3Cbr%3E%3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3C/p%3E%0A%3Cp%3E%3Cb%3EBENEFITS%3C/b%3E%3Cbr%3EUT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:%3C/p%3E%0A%3Cul%3E%0A%3Cli%3EPPO medical plan, available day one at no cost for full-time employee-only coverage%3C/li%3E%0A%3Cli%3E100% coverage for preventive healthcare-no copay%3C/li%3E%0A%3Cli%3EPaid Time Off, available day one%3C/li%3E%0A%3Cli%3ERetirement Programs through the Teacher Retirement System of Texas (TRS)%3C/li%3E%0A%3Cli%3EPaid Parental Leave Benefit%3C/li%3E%0A%3Cli%3EWellness programs%3C/li%3E%0A%3Cli%3ETuition Reimbursement%3C/li%3E%0A%3Cli%3EPublic Service Loan Forgiveness (PSLF) Qualified Employer%3C/li%3E%0A%3Cli%3E%3Ca href=%22http://jobs.utsouthwestern.edu/benefits/#top%22 target=%22_blank%22 rel=%22noopener%22%3ELearn more about these and other UTSW employee benefits!%3C/a%3E%3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cbr%3E%3Cbr%3E%3Cb%3E%3Cb%3EEXPERIENCE AND EDUCATION%3C/b%3E%3C/b%3E%3Cbr%3E%3Cb%3ERequired%3C/b%3E%3Cb%3E%3C/b%3E%3C/p%3E%0A%3Cul%3E%0A%3Cli%3E%3Cb%3EEducation%3C/b%3E%3Cbr%3EPhD with major course work in the field of assignment or %3Cbr%3EMaster%27s Degree with major course work in the field of assignment or %3Cbr%3EBachelor%27s Degree with major course work in the field of assignment %3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cb%3E%3C/b%3E%3C/p%3E%0A%3Cul%3E%0A%3Cli%3E%3Cb%3EExperience%3C/b%3E%3Cbr%3E5 years of research experience in the field of assignment with PhD and 2 years at the level of Senior Research Associate or its equivalent or %3Cbr%3E7 years of research experience in the field of assignment with Master%27s degree. and 3 years at the level of Senior Research Associate or its equivalent or %3Cbr%3E9 years of research experience in the field of assignment with Bachelor%27s degree. and 4 years Level of Senior Research Associate or its equivalent. %3C/li%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cbr%3E%3Cb%3E%3Cb%3EJOB DUTIES%3C/b%3E%3C/b%3E%3C/p%3E%0A%3Cul%3E%0A%3Cul%3E%0A%3Cli%3EPlans, organizes coordinates, directs, and personally participates in assigned scientific or medical research project. Selects or assists in selection of key research personnel. Determines specific goals or objectives to be attained. Assigns and reviews work of subordinates. Plans experimental protocols.%3C/li%3E%0A%3Cli%3EReviews and analyzes resulting research data. Revises techniques or approaches to work problems as indicated necessary by research data.%3C/li%3E%0A%3Cli%3ECompiles, writes, and submits research results to supervisor. Prepares or assists in preparation of research papers, reports, and abstracts for publication as one of co-authors.%3C/li%3E%0A%3Cli%3EDesigns, develops, or adapts equipment used in experiments or research to obtain desired results.%3C/li%3E%0A%3Cli%3EPlans and supervises training of technicians and other laboratory personnel with respect to proper laboratory techniques, use of laboratory equipment, and safety procedures.%3C/li%3E%0A%3Cli%3ESupervises group of employees of lower grade engaged in performance of technical and professional work, which vary from routine to complex laboratory work tasks.%3C/li%3E%0A%3Cli%3EMay confer with industrial, governmental, or other groups concerning progress or results of research project.%3C/li%3E%0A%3Cli%3EPerforms other duties as assigned.%3C/li%3E%0A%3C/ul%3E%0A%3C/ul%3E%0A%3Cp style=%22font-family: Arial;%22%3E%3Cbr%3E%3Cb%3E%3Cb%3ESECURITY AND EEO STATEMENT%3C/b%3E%3C/b%3E%3Cbr%3E%3Cb%3ESecurity%3C/b%3E %3Cbr%3EThis position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.%3Cbr%3E%3Cbr%3E%3Cb%3EEEO Statement%3C/b%3E%3Cbr%3EUT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.%3C/p%3E
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