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Institute Associate Scientist III in United States, Texas, Houston, Houston (TX Med Ctr) bei MD Anderson Cancer Center

MD Anderson Cancer Center · Houston, Vereinigte Staaten Von Amerika · Hybrid

76.650,00 $  -  114.975,00 $

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Research
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176482 Requisition #

The Institute Associate Scientist III will apply technical expertise and experience to plan, coordinate, design, assist, and supervise the implementation of research projects in the laboratory, the evaluation and interpretation of research data, and the quality of resulting publications. Assist with optimization of assays/equipment used in experiments or research to obtain desired results. Compiles and submits reports to superior. Supervises the training of technicians and other laboratory personnel with respect to proper laboratory techniques, the use of laboratory equipment and safety procedures.

Image Acquisition Functions

  • Perform imaging and qualitative/quantitative image analysis of immunohistochemistry (IHC) and immunofluorescence (IF) stained slides.
  • Optimize and perform multiplex IF methods/technologies in assays including CODEX, DSP GeoMx, CosMx, Visium) and their practical application in IMT’s projects.
  • Independently organizes, coordinates, directs and participates in scientific research projects.

Spatial Analysis Functions

  • Perform spatial assays and analyses including Nanostring GeoMX DSP and CosMx to run projects on protein profiling in FFPE tissues and assist with preparation of scientific figures.
  • Customize and implement published image analysis algorithms and protocols for tissue segmentation, cell quantification, and biomarker expression.
  • Participate in optimization and implementation of newer spatial molecular profiling technology for clinical trial projects.
  • Perform and implement an image analysis workflow for both brightfield and multiplex IF images using numerous image analysis and data analysis software such as Halo, QuPath, R Studio, Python, visiopharm and CytoMap/MatLab.
  • Follow the current scientific literature for recent spatial analysis trends and evaluate new spatial analysis technologies to assess their implementation ability with the current in-house analysis pipeline.
  • Actively participate in the testing of pathology image management and analysis systems, tools and technology.
  • Train peers and junior lab members on image analysis and QC criteria.

Key Laboratory Functions:

  • Organizes and assists with analysis using R studio, python of data from the different clinical trials to be presented at different meetings
  • Maintain records of runs and updated SOPs to be used in the lab.
  • Plans and supervises the training of technicians and other laboratory personnel with respect to proper laboratory techniques, the use of equipment, and safety procedures.
  • Monitors patients' tissue samples being used for different spatial assays for collective downstream data analysis.
  • Perform other tasks as assigned.

EDUCATION: 
Required: Bachelor's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field. Three years of relevant research experience in lab. With preferred degree, one year of required experience. 

Preferred: PhD in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. 

EXPERIENCE: 
Required: Three years relevant research experience in a lab. One year experience with preferred degree. 

Preferred: Big Data Analyst, Benchwork experience, and Genomic data experience. 

The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state, or local laws unless such distinction is required by law.http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

Additional Information
  • Requisition ID: 176482
  • Employment Status: Full-Time
  • Employee Status: Regular
  • Work Week: Day/Evening
  • Minimum Salary: US Dollar (USD) 76,650
  • Midpoint Salary: US Dollar (USD) 95,300
  • Maximum Salary : US Dollar (USD) 114,975
  • FLSA: exempt and not eligible for overtime pay
  • Fund Type: Soft
  • Work Location: Hybrid Onsite/Remote
  • Pivotal Position: Yes
  • Referral Bonus Available?: Yes
  • Relocation Assistance Available?: Yes

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