Scientist III, Process Development - Downstream bei Matica Biotechnology

Matica Biotechnology is at the forefront of biopharmaceutical research and development. The Matica Bio team brings an average of 15 years of cell and viral vector manufacturing experience to the development and manufacture of advanced therapy products. At our purpose-built GMP facility in College Station, Texas, we provide rapid development and scale-up of cell and gene therapies, vaccines, and Oncolytics meeting worldwide regulatory compliance.

The true value of a CDMO is determined by the quality of its people. Matica Bio consists of a dedicated team of experts. We’re a cell and gene therapy CDMO powered by people, and our people provide real benefits to the quality, safety and speed of the cell and gene therapy development pathway. Our inventive thinking and foresight help us strategize the best path to take therapies from the lab to the market. Come join our dedicated team and Make it Happen With Matica!

Position Opportunity:

The Scientist III Downstream Process Development is involved in the development and optimization of processes to facilitate manufacturing and meet client requirements. The individual will contribute to Process Development within a project team to provide experimental design and planning and work in the development, evaluation, and characterization of downstream processes to produce novel therapeutic products. Collaborate between and act as a technical SME for associated departments and client representatives. 

How you will make an impact:

• Identify, design, execute and analyze experimental protocols and present results to senior leadership, clients, and team members. 
• Authoring and revision of: SOPs, batch records, data presentations, study design and protocols.
• Able to lead onboarding and training of new team members and assist in the recruitment and interviewing of potential team members.
• Serve as an SME for downstream process development AND/OR special equipment for PD. 
• Operate and maintain a variety of lab equipment including but not limited to FPLC, TFF, scales, tubing welders/sealers and pH/conductivity meters.
• Maintain lab cleaning procedures to ensure a state of control.  
• Operate and maintain a variety of lab consumables and reagents.
• Lead in the technology transfer process to enable clinical manufacture, using novel processes, within the GMP environment. This may require direct involvement in clinical manufacture as an SME.
• To assess manufacturing processes supplied by client companies for suitability for GMP manufacture and identify any scale-up requirements/issues.
• Provide feedback to leadership on the set up, execution and analysis of experimental protocols and technical reports.
• Provide input for improvements to department methods, documentation, procedures, and safety.         
• Independently research and propose innovative solutions and ideas and share with the department.
• Support Supervisor and leadership by assisting with task including but not limited to budget management (INFOR), and scheduling.
• Maintain good communication across the team and to leadership.
• Perform other duties as required.

As a future Matican you bring:

Education

• Bachelor’s degree minimum in a scientific discipline e.g., Biology, biochemistry, Virology, etc.

Experience

• 6+ years in a Process Development role with cGMP experience, in the biotech industry.  
• OR 4+ years in a Process Development role with cGMP experience, in the biotech industry with master’s degree or Ph.D.
• Consideration will be given to relevancy and quality of the job experience. 

Skills

• Ability to Identify, design, execute and analyze experimental protocols 
• Ability to authorize and revise: SOPs, batch records, data presentations, study design and protocols
• Ability to operate and maintain a variety of lab equipment including but not limited to FPLC, TFF, scales, tubing welders/sealers and pH/conductivity meters.
• Collaborative team player 
• Attention to detail
• Ability to wear appropriate PPE 
• Good verbal and written communication skills
• Integrity, discretion and confidentiality
• Computer software skills, organization, record keeping and planning
• Ability to maintain clean room facilities 

Qualities & Attitude

• Strong work ethic with good written and oral communication.
• Ability to work collaboratively within a team and across departments. 
• Proactive and self-motivated. 

Competencies we look for:

Commitment to Excellence, Problem Solving/Decision Making/Analytical Thinking, Communication Skills, Teamwork/Cooperation/Supportiveness, Flexibility/Adaptability, Initiative/Taking Ownership, Focus on Safety, Ethical/Trustworthiness, Work Ethic/Reliability, Thoroughness, Customer Service

We Value:

Matica’s Values are at the forefront of everything we do, our culture, and the decisions we make. 

• Start with Safety & Quality 
• Choose the Path of Openness, Honesty, and Integrity
• Nurture Our Differences to Enable Our Collective Success
• Learn Continuously to Ensure Our Value and Relevance
• Commit to Delivering Life Altering Therapies