Scientist, Next Generation Sequencing (NGS) bei Verve Therapeutics, Inc.

The Position

We are seeking a passionate and detail-oriented Scientist to join our fast-paced Next-Generation Sequencing (NGS) team, supporting the execution of high-quality library preparation and sequencing workflows for multiple gene editing and molecular biology projects. This is an exciting opportunity to gain hands-on experience in a collaborative environment, contributing to groundbreaking scientific research while working under the guidance of subject matter experts. The ideal candidate will demonstrate strong technical skills, adaptability, and a growth mindset, taking initiative in laboratory operations, assisting in the onboarding of new assays and instruments, and actively contributing to cross-functional research initiatives that advance innovative gene editing technologies.  This is a lab-based role and requires a minimum of 4-days on-site each week.

Job Responsibilities

• Conduct, and troubleshoot experiments in alignment with SOPs and expert guidance, including independent preparation of high-quality next-generation sequencing libraries for diverse applications using both automated (e.g., Bravo, Hamilton) and manual methods.
• Operate and maintain laboratory instruments including Illumina sequencers, long-read sequencing platforms such as PacBio, and ancillary equipment such as Fragment Analyzer, TapeStation and qPCR systems among others.
• Perform data analysis, manage results, and ensure rigorous documentation practices aligned with Good Documentation Practices (GDPs).
• Author protocols, technical reports, and summaries, presenting findings to cross-functional teams and stakeholders.
• Contribute to the evaluation and integration of new technologies and assay improvements to enhance sequencing workflows, data quality, and scientific rigor through innovation and literature-based insights.
• Partner cross-functionally with lab teams, bioinformatics, and project stakeholders to coordinate timelines and activities.
• Maintain a safe, efficient lab environment through good equipment maintenance and strict adherence to provided SOPs.
• Thrive in a fast-paced, dynamic environment by balancing multiple priorities, maintaining high standards of quality and organization, and demonstrating initiative in personal growth through continuous learning.
• Collaborate effectively across functions, foster an inclusive team culture, and contribute to shared goals by supporting others’ development and driving continuous process improvement.
• Other duties as assigned.

Qualifications

• Education & Experience
  • Bachelor’s degree in relevant scientific discipline.
  • 1-3 years relevant industry experience required.
  • Experience in amplicon sequencing or the use of NGS for high-throughput screening is a plus.
  • Experience with Illumina library preparation is a plus.
• Skills & Abilities
  • Ability to execute experiments at the bench, analyze data, and prepare comprehensive reports.
  • Ability to leverage critical thinking and problem-solving skills for data troubleshooting.
  • Exceptional written and verbal communication skills, with the ability to clearly articulate technical concepts to diverse audiences.
  • Ability to adhere to protocols and Good Laboratory Practices (GLPs).
  • Ability to use statistical analysis tools and standard productivity software (e.g., Word, Excel).
  • Ability to work independently or as part of a team, managing multiple projects and adapting to shifting priorities.
  • Active listener who fosters open communication, values diverse perspectives, and creates an inclusive environment.
  • Proactively challenges established norms, embraces change, and learns from mistakes to overcome obstacles.
  • Committed to achieving high-quality results with integrity while fostering strong team collaboration and supporting others.
  • Celebrates team successes, motivates others, and creates a supportive, collaborative atmosphere.
  • Strong attention to detail, ensuring accurate data production and thorough documentation.
  • Excellent organizational skills, capable of managing multiple tasks simultaneously while meeting deadlines.