Research Scientist II/III, DNA Synthesis bei GenScript/ProBio
GenScript/ProBio · Redmond, Vereinigte Staaten Von Amerika · Onsite
- Senior
- Optionales Büro in Redmond
About GenScript
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
About ProBio
ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy, vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio’s total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing.
Job Scope:
We are seeking an experienced Scientist with a multi-disciplinary background, specifically in the areas of oligonucleotide synthesis, organic/bioorganic synthesis, surface functionalization, and molecular biology. Successful candidates may also have knowledge and experience with photochemistry, and nucleic acid chemistry. This position will involve research and collaboration with scientists and engineers improving the company’s proprietary semiconductor DNA synthesis technology and developing various diagnostic applications.
Location: Redmond, WA
Responsibilities:
- Develop and synthesis of desired organic compound
- Select and employ analytical techniques for synthesized compound
- Develop and perform on machine oligo synthesis with various modifications
- Develop surface functionalization for metal and non-metal surfaces for solid phase oligonucleotide synthesis
- Select and employ analytical techniques for surface characterization
- Explore methods toward enhancing surface stability and functional loading
- Contribute knowledge and expertise in the field of nucleic acid chemistry, specifically phosphoramidite based oligonucleotide synthesis.
- Technology transfer to the production team and support as needed for process improvement or troubleshooting
- Perform statistical data analysis and present the results
Qualifications
- Ph.D. in Organic Chemistry, Biochemistry, Chemical Biology, or a related field; or M.S. with a minimum of 3 years of relevant industry experience.
- Expertise in nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
- Strong foundation in organic chemistry and photochemistry.
- In-depth understanding of nucleic acid chemistry and phosphoramidite-based synthesis.
- Hands-on experience with total synthesis, including a variety of purification techniques such as column chromatography, HPLC, and Biotage systems.
- Demonstrated proficiency in handling sensitive or delicate materials (preferred).
- Familiarity with laboratory automation tools and platforms (a plus).
- Advanced molecular biology skills, including PCR, qPCR, hybridization assays, and next-generation sequencing (NGS).
- Proven track record of effective collaboration within interdisciplinary and cross-functional teams.
- Results-driven, with a proactive, hands-on approach to experimental design and problem-solving.
- Excellent written and verbal communication skills.
- Strong documentation skills for drafting technical reports, summarizing experimental data, and supporting technology transfer to manufacturing.
- Highly self-motivated and passionate about driving innovation in the field of biotechnology.
Benefit:
- Medical Insurance/ Vision Insurance/ Dental Insurance
- 401(k) & Retirement Savings Plan (RSP)
- Short Term Disability Insurance
- New Child Leave
- Paid Time Off
- Paid Company Holidays per year
- Paid Sick Days (earned based on hours worked)
- Compassionate Leave
- Jury Duty Leave
- Float day
- Personal days
Perks:
- Free colleague meals during shift
- Onsite massages Charis
- Onsite gyms
Compensation:
Salary range: $80,000 – $110,000, depending on experience and qualifications.
GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
Please note: Genscript USA Inc./ProBio Inc. will only contact candidates through verified application sources. GenScript/Probio does not request personal information from candidates through individual email or any other platform.
