Postdoctoral Scientist bei Texas Biomedical Research Institute

Description

We are seeking a highly motivated postdoctoral researcher to join our team studying the epigenetic mechanisms of HIV neuropathogenesis. This position will also explore the use of novel neurotechnologies to deliver long-acting antiretroviral therapies (LA-ART) and gene therapeutics to the brain using the simian immunodeficiency virus (SIV)-infected rhesus macaque model.

Current projects include:

• Investigating how cannabinoids modulate neuroinflammation in HIV/SIV infection through epigenetic mechanisms.
• Developing and testing new methods to increase blood-brain barrier permeability for improved delivery of LA-ART and enhanced viral suppression.

The Role:

• Design and conduct molecular and cellular experiments.
• Perform and troubleshoot a wide range of techniques, including tissue cell isolation, DNA/RNA extraction, qPCR, cloning, single-cell/nuclei RNA/ATAC-seq, immunoprecipitation, western blotting, luciferase assays, multi-color flow cytometry, in situ hybridization, immunofluorescence, and data analysis.
• Generate, interpret, and present data.
• Contribute to manuscript preparation and publication.
   

Our Ideal Candidate:

• A highly motivated candidate with a PhD, MD, or DVM in a related field.
• Strong background in neuroscience research preferred.
• Experience with neurotechnologies such as focused ultrasound or fMRI (data acquisition and analysis) is a significant plus.
• Demonstrated ability to work independently and collaboratively.

This role offers the opportunity to contribute to cutting-edge translational research with direct implications for improving HIV therapies.

Who We Are:

Join our incredible mission to pave the way for a world free from the fear of infectious disease!

Texas Biomedical Research Institute is pioneering and sharing scientific research to protect you, your families, and our global community from the threat of infectious diseases. Our scientific discoveries create breakthroughs in medical research to provide better overall global health.

Texas Biomed is the only independent, nonprofit infectious disease research institute in the U.S. to combine:

• The highest-level biocontainment labs for infectious disease and biodefense research
• A federally-designated National Primate Research Center
• More than 80 years of discoveries advancing diagnostics, vaccines and therapies
• An entrepreneurial culture and specialized expertise in regulated science required for FDA approval

What We Can Offer You:

• Recognized as one of the San Antonio Business Journal’s Best Places to Work in 2025.
• Awarded the 2024 Healthy Workplace Platinum Recognition by the San Antonio Business Group on Health (SABGH).
• Employee-centered culture focused on open communication, job empowerment, and trust.
• Comprehensive health, dental, vision, and life insurance plans for you and your family (including your pets!).
• Competitive employer-funded retirement plan with 7% contributions starting on day one, increasing with years of service.
• Generous paid time off, including 14 paid holidays and a paid Winter Recess (last week of December until New Year’s).
• On-site medical clinic, wellness incentives, and paid prescription drug resources to support your health.
• On-site gym and wellness programs to help you stay active.
• Flexible work arrangements designed to support work-life balance.
• We offer a relaxed dress code so you can feel comfortable and be yourself at work.
• Dynamic learning environment with professional development, mentorship, tuition reimbursement, and leadership programs to help you grow.

We take pride in fostering a culture of respect, opportunity, and unity. Texas Biomedical Research Institute provides equal employment opportunities for all qualified employees and applicants without regard to race, color, sex, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.