- Bureau à San Francisco
Description
About Becoming
Becoming is building Developmental Intelligence: AI for predicting how organisms change over time.
Most experimental systems fail when metabolic demands become too high. We are building systems that don’t — enabling sustained, controllable biological processes over long time horizons so that development, adaptation, and failure can be observed, perturbed, and predicted.
Physiology is central to this effort. Without stable, well-characterized physiological function, long-horizon prediction is impossible.
The Role
We are hiring a Developmental Physiologist to own and advance the functional and metabolic performance of developing biological systems within Becoming’s platform.
This role is for someone who thinks in systems, not endpoints — someone who understands how transport, metabolism, signaling, mechanics, and homeostasis interact over time. You will help define what “physiologically stable” and “physiologically meaningful” actually mean in sustained developmental systems.
This is a high-agency role. You will not be handed protocols to run. You will be expected to define measurements, interpret dynamics, and drive improvements in system-level function.
What You’ll Own
- Definition and measurement of physiological function over time in developing biological systems
- Characterization of metabolic demand, exchange, and stability under sustained operation
- Design of assays and readouts for oxygenation, nutrient utilization, waste removal, and energy balance
- Interpretation of how physiological variables influence developmental trajectories and system behavior
- Identification of failure modes when systems lose stability — and strategies to prevent them
- Close collaboration with biology, hardware, and modeling teams to align physiology with system design
- Translation of physiological complexity into clear, decision-relevant signals
Who You Are
You are someone who:
- Operates with high agency — you identify what needs to be measured and why
- Takes ownership of outcomes, not just data collection
- Brings high energy to complex, dynamic biological systems
- Acts with high integrity — you are honest about uncertainty, limits, and tradeoffs
- Communicates directly and clearly, especially when systems are not behaving as expected
- Is self-aware about your strengths and gaps, proactively fills them and open to feedback
- Thinks like a systems integrator, not a siloed specialist
- Is comfortable working where physiology, engineering, and modeling intersect
Requirements
Required
- PhD or equivalent experience in physiology, developmental biology, biomedical sciences, or a related field
- At least 1 year of industry experience (biotech, pharma, startup, or applied research environment)
- Strong grounding in developmental or integrative physiology
- Experience reasoning about metabolism, transport, homeostasis, and functional performance
- Ability to design measurements where signals are dynamic, multivariate, and context-dependent
- Comfort working in fast-moving environments with incomplete information
Strong Signals
- Experience with long-term or perfused biological systems
- Background in metabolic physiology, vascular physiology, or systems-level biology
- Experience linking physiological measurements to predictive or computational models
- Track record of moving beyond descriptive readouts to mechanistic understanding
Benefits
- Competitive salary and meaningful equity
- Full benefits
- High-trust, high-ownership environment
- Rapid growth in scope and responsibility
