%3Cp class=%22p1%22%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Cstrong%3EResearch Assistant Professor Position%3C/strong%3E%3Co:p%3E%3C/o:p%3E%3C/span%3E%3Cbr%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Cstrong%3EDepartment of Pharmacology and Chemical Biology%3C/strong%3E%3Co:p%3E%3C/o:p%3E%3C/span%3E%3Cbr%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Cstrong%3EUniversity of Pittsburgh School of Medicine%3Co:p%3E%3C/o:p%3E%3C/strong%3E%3C/span%3E%3C/p%3E%3Cp class=%22p1%22%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Co:p%3E%3C/o:p%3E%3C/span%3E%3C/p%3E%3Cp class=%22p1%22%3E%3Cspan style=%22font-size:11.0pt;%22%3EA Research Assistant Professor position in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh is immediately available in the laboratory of Dr. Adam Straub. Research in the Straub laboratory centers on endothelial redox biology and vascular remodeling. %3C/span%3E%3Cspan style=%22color:windowtext;font-size:11.0pt;%22%3EThe position will investigate how cytochrome b5 reductase 4 (CYB5R4) sustains nucleotide balance to support endothelial proliferation and ischemia-induced angiogenesis, and how these mechanisms influence atherosclerosis and inflammation. Approaches include mechanistic studies in cultured endothelial cells and mouse models, integrated multi-omics (e.g., bulk and single-cell RNA sequencing, metabolomics, proteomics), quantitative imaging and causal inference, and targeted gene-delivery/rescue strategies. The long-term goal is to translate redox-metabolic mechanisms into therapeutic strategies for vascular disease. The incumbent will be encouraged to apply for grants and develop an emerging, complementary research program.%3Co:p%3E%3C/o:p%3E%3C/span%3E%3C/p%3E%3Cp class=%22p1%22%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Co:p%3E%3C/o:p%3E%3C/span%3E%3C/p%3E%3Cp%3E%3Cspan style=%22font-family:%26quot;Aptos%26quot;,sans-serif;font-size:11.0pt;%22%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3ECandidates should have 5+ years of postdoctoral research experience, a strong publication record, and demonstrated expertise in endothelial/vascular biology and redox or metabolic signaling, including experience with%3C/span%3E%3Ci%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3E in vitro %3C/span%3E%3C/i%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3Eand %3C/span%3E%3Ci%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3Ein vivo%3C/span%3E%3C/i%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3E models, intermediate to advance programming/bioinformatics skills, along with excellent written and oral communication skills. Salary is commensurate with experience. To apply for the position, qualified candidates with a PhD in biochemistry, genetics, cell biology, or a related discipline are invited to complete an application in %3C/span%3E%3Cspan class=%22s1%22 style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:%26quot;DengXian Light%26quot;;mso-fareast-language:EN-US;mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin;%22%3ETalent Center at %3C/span%3E%3C/span%3E%3Ca href=%22https://www.join.pitt.edu/#25006051%22%3E%3Cspan style=%22font-family:%26quot;Aptos%26quot;,sans-serif;font-size:11.0pt;%22%3E%3Cspan class=%22s1%22 style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:%26quot;DengXian Light%26quot;;mso-fareast-language:EN-US;mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin;%22%3Ehttps://www.join.pitt.edu/#25006051%3C/span%3E%3C/span%3E%3C/a%3E%3Cspan style=%22font-family:%26quot;Aptos%26quot;,sans-serif;font-size:11.0pt;%22%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%26quot;Times New Roman%26quot;;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3E.%26nbsp;%3C/span%3E%3C/span%3E%3C/p%3E
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