Postdoctoral Researcher - Metabolic Physiology chez Lilly

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

We serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries begin in Lilly Research Laboratories, where our scientists create new medicines to address the world’s greatest health challenges.

Postdoctoral scientists help us continue this pursuit. During your experience you will receive:

• Top-tier industry research experience.
• Mentorship from Lilly’s leading scientists.
• Laboratory training and education to support your development.
• Opportunities for collaboration and networking across a vibrant community of postdoctoral scientists and researchers.

We are seeking an ambitious post-doctoral scientist with strong research and communication skills to join the Obesity Research group in Boston. The successful candidate will contribute to a highly collaborative drug discovery and development team focused on anti-obesity therapeutics. This role emphasizes hepatic and adipose tissue biology, inter-organ crosstalk, and metabolic regulation. The candidate will harness a strong cell culture background, in vivo expertise, and complementary wet lab experience to support discovery efforts and pipeline projects.

Responsibilities

• Design and implement in vitro and in vivo experiments to evaluate metabolic pathways and mechanisms of action in obesity, diabetes, and related metabolic disorders.
• Develop and optimize cellular models of hepatic and adipose tissue biology, including co-culture systems and organoid platforms, using human or mammalian, immortalized, primary, or iPSC-derived cell lines.
• Apply metabolic tracing techniques and flux analysis to dissect nutrient utilization, lipid metabolism, and endocrine signaling across tissues.
• Use animal models of metabolic disease to investigate physiological responses and validate therapeutic hypotheses
• Perform molecular and biochemical assessments (e.g., molecular cloning, qPCR, ELISA, Western blot) on in vitro, ex vivo, and in vivo samples in collaboration with cross-functional teams.
• Maintain accurate records, conduct independent data analysis, and communicate findings in written and oral formats.
• Present novel methods and discoveries at scientific conferences and publish in high-impact peer-reviewed journals.

Basic Qualifications

Ph.D. in cellular and molecular biology, physiology, or biomedical sciences or related degree

Additional Skills/Preferences

• Expertise in hepatic and adipose tissue biology and physiology.
• Experience with human or mammalian cell culture systems.
• Demonstrated proficiency in in vivo experimentation and animal models of metabolic disease.
• Advanced skills in metabolic tracing and flux analysis.
• Self-directed and highly motivated with a commitment to continuous learning and scientific excellence.
• Strong communication skills with experience presenting research findings.
• Proven track record of impactful contributions to research projects, supported by first or co-authorship in peer-reviewed journals.
• High learning agility and adaptability to new scientific concepts and operational systems.
• Collaborative mentality with a history of productive interdisciplinary teamwork.

Additional Information

This position is for a fixed duration of two years, with the potential to extend to three years and a maximum of four years. There will be an opportunity to apply for full-time positions upon completion of the postdoctoral term.

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Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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