Intern, Multi-tissue Systems Engineering Team at IHB (Institute of Human Biology) Basel, Switzerland Research and Discovery presso Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed. This position is located at the Institute of Human Biology (Zurich site), a department within pRED, where the establishment of human model systems for drug discovery and personalized medicine is a primary focus. At the IHB, we bring together areas of tissue engineering, microtechnologies, organoid development and phenotyping to fuel scientific discovery. 

Internship mission

We are offering a challenging and rewarding opportunity for a laboratory intern to work on ex vivo model development and drug testing using patient-derived tissue explant cultures. In this role, you will contribute to our efforts on harmonizing explants for long term culture with de novo vascularization on chip, for asking questions in cancer biology, as well as drug testing. You will optimize novel culture workflows in conjunction with existing quantitative methods such a s flow cytometry, microscopy and sequencing. In this position, you will have the unique opportunity to help push explant technology forward while also interacting with the wider IHB and pRED community.  

Your Impact

• Supporting our scientific efforts through hands-on lab work and troubleshooting.

• Analyzing and interpreting data. 

• Contributing to data presentation and manuscript/SOP writing

Your Profile

You enjoy being part of a team in a dynamic, inclusive environment which gives you full accountability for your own contributions and development. You are goal-oriented, resourceful and flexible in problem solving. You are used to working with colleagues of different expertise levels and you take a keen interest in the scientific aspect of the projects you contribute to. You have experience in cell culture assay execution and are excited to adapt these assays for the specific task at hand. You are an active listener, are open and clear when communicating and easily connect with people around you. 

Specifically, you:

• Hold a BSc in biology, bioengineering or related field

• Have solid experience in cell culture, preferably in the context of primary material and organoids. 

• Are fluent in English and have excellent documentation skills.

Additionally, any of the following are beneficial:

• Experience with on-chip/microsluidic cultures 

• Experience with endothelial cell cultures

• Knowledge of immunostaining and confocal microscopy (on live, fixed or cleared samples)

• Experience in multichannel flow cytometry

Our commitment

Roche commits to recognising talent and aptitude. We prioritize encouraging and supporting our employees in their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds,

perspectives, and skills. The more inclusive we are, the better our work will be.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.