Hybrid Research Instructor - Full-Time presso University of Pittsburgh

%3Cp class=%22p1%22%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Cstrong%3EResearch Instructor Position%3C/strong%3E%3C/span%3E%3Cbr%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Co:p%3E%3C/o:p%3E%3Cstrong%3EDepartment of Pharmacology and Chemical Biology%3C/strong%3E%3C/span%3E%3Cbr%3E%3Cspan style=%22font-size:11.0pt;%22%3E%3Co:p%3E%3C/o:p%3E%3Cstrong%3EUniversity of Pittsburgh School of Medicine%3Co:p%3E%3C/o:p%3E%3C/strong%3E%3C/span%3E%3C/p%3E%3Cp class=%22p1%22%3E%3Cspan style=%22font-family:%27Aptos%27,sans-serif;font-size:11.0pt;%22%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3EA Research Instructor position in the Department of Pharmacology and Chemical Biology at the University of Pittsburgh is immediately available in the laboratory of Dr. Orlando Schärer. Research is focused on the interplay of DNA repair pathways and anticancer therapies. The aim is to investigate how the nucleotide excision repair (NER) pathway processes DNA adducts formed by antitumor agents such as cisplatin or trabectedin. The project involves biochemical, cell biological and structural studies of how NER protein interact with damaged DNA to excise lesions formed by anticancer agents. The long-term goal is to leverage mechanistic insights into NER to improve anticancer therapies. The incumbent will have the opportunity to apply for grants and ultimately develop their own research program.%3C/span%3E%3C/span%3E%3C/p%3E%3Cp class=%22p1%22%3E%3Cspan style=%22font-family:%27Aptos%27,sans-serif;font-size:11.0pt;%22%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3EThe candidate is expected to have conducted several years of postdoctoral research, strong publication record, experience in studying genome maintenance pathways, and excellent written and oral communication skills. Salary is commensurate with experience. To apply for the position, qualified candidates with a PhD in biochemistry, genetics, cell biology of a related discipline are invited to complete an application in %3C/span%3E%3Cspan class=%22s1%22 style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:%27Times New Roman%27;mso-fareast-language:EN-US;mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin;%22%3ETalent Center at %3C/span%3E%3C/span%3E%3Ca target=%22_blank%22 rel=%22noopener noreferrer%22 href=%22https://www.join.pitt.edu/#25003671.%22%3E%3Cspan style=%22font-family:%27Aptos%27,sans-serif;font-size:11.0pt;%22%3E%3Cspan style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:Aptos;mso-fareast-language:EN-US;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;%22%3Ehttps://www.join.pitt.edu/#25003671%3C/span%3E%3Cspan class=%22s1%22 style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:%27Times New Roman%27;mso-fareast-language:EN-US;mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin;%22%3E.%3C/span%3E%3C/span%3E%3C/a%3E%3Cspan style=%22font-family:%27Aptos%27,sans-serif;font-size:11.0pt;%22%3E%3Cspan class=%22s1%22 style=%22line-height:115%;mso-ansi-language:EN-US;mso-ascii-theme-font:minor-latin;mso-bidi-font-family:%27Times New Roman%27;mso-bidi-language:AR-SA;mso-bidi-theme-font:minor-bidi;mso-fareast-font-family:%27Times New Roman%27;mso-fareast-language:EN-US;mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin;%22%3E%26nbsp;%3C/span%3E%3C/span%3E%3C/p%3E

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