Hybrid Vice President, RAP-314 Program Leader presso Rapport Therapeutics

Your impact:
In this enterprise leadership role you will lead a cross-functional team to develop the integrated development plan for RAP-314, a foundational program in the company’s pipeline, a program with the potential to improve the lives of millions of patients living with pain and create significant value for RAPP.

Your day-to-day:

• Serve as the single accountable leader for RAP-314 from early-stage development through through Phase 2/3 and registration.
• Opportunity to shape and lead integrated development plan for RAP-314 from IND through product approval.
• Define and drive the integrated development strategy, ensuring alignment with target product profile, global regulatory expectations, and corporate goals.
• Lead program-level decision-making, risk assessment, and scenario planning in coordination with senior leadership.
• Lead and align cross-functional teams including clinical, regulatory, CMC, biometrics, and medical affairs.
• Provide innovative and flexible operational solutions and options to the cross functional and development teams; assist in preparing scenarios for creative solutions to operational challenges.
• Oversee timelines, budgets, and resources across functions to ensure milestones are met.
• Oversee preparation of key regulatory filings (IND amendments, End-of-Phase 2 meetings, NDA/MAA submissions).
• Represent the program in regulatory agency meetings alongside clinical and regulatory leads.
• Present program updates, timelines, risks, and mitigation plans to the executive leadership team, board of directors, and investors.
• Build strong relationships with key internal stakeholders and external partners (CROs, CDMOs, consultants, etc.).

Must-Haves:

• PhD, PharmD, MD, or equivalent advanced degree in a relevant scientific or clinical field.
• 15+ years of biotech/pharmaceutical industry experience, with proven leadership in small molecule drug development.
• Significant experience leading cross-functional programs through early and middle stages of development (Phase 1/2) and toward regulatory approval.
• Demonstrated success in program leadership roles, particularly startup biotech environments.
• Strong understanding of regulatory pathways and expectations for small molecule therapeutics.
• Exceptional interpersonal, communication, and influencing skills.
• Experience managing complex timelines, budgets, and partner relationships.
• Familiarity with working across multiple geographies (e.g., US and EU regulatory bodies).
• Experience managing/mentoring in a highly matrixed environment

What makes Rapport special:

• Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.
• We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
• Your perspective matters. Stick your neck out, share your ideas – we work as a team.
• We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with.
• Leadership that CARES – about you, your growth + development.
• We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
• Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!
• You get to be YOU! Show up as you are and make every day count.

*This role is based in Boston, MA with a hybrid work schedule*