Hybrid Senior Scientist Clinical Histopathology (m/f/d) at Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation.

Our Vision is to develop curative medicines for cancer patients. Our Mission is to transform pioneering scientific discoveries into effective medicines. pRED Oncology focuses on 3 key areas of expertise: Cancer Immunotherapy, Cancer Cell Target and Tumor Micro-environment.

The Early Development Oncology (EDO) Team is responsible for identification and validation

of candidate biomarkers used for demonstration of pharmacodynamic effects and mechanism-of-action, as well as for response prediction and patient selection / stratification. EDO will make use of available technologies such as flow cytometry, RNA seq, genomics, Immunohistochemistry, etc, applied to clinical specimens from exploratory early stage trials. The EDO Team supports the whole oncology portfolio and closely interacts with Discovery and Early Clinical Development.

Job mission

Histopathology activities required by EDO are performed by external Contract Research Organizations (CROs). The scientists (m/f/d) within the Clinical Histopathology team are highly technical experts that coordinate interactions between internal biomarker experts and the external vendors, with an emphasis on histopathology outsourcing requests.

Histopathology biomarker projects may include outsourcing an IHC assay establishment for use in early clinical trials, outsourcing a target assessment or prevalence request for a new candidate biomarker, coordinate external acquisition of pathology data sets (images and/or blocks) in support of reverse translation digital pathology request, among others.

Your impact

• Discuss and document the scientific scope, requirements and project deliverables
• Work with external partners to define and manage timelines and resources
• Oversee the execution of the project to meet technical and quality expectations
• Ensure relevant biomarker data is made available within the approved timelines
• Support the integration and scientific interpretation of the external data received

Your profile

You thrive in and are dedicated to establishing a culture of mutual support, cross-training, continuous learning and self-organization to meet project and functional goals. Furthermore, you know how to prioritize, how to create clarity and focus. Besides, you have the following education and experience: 

• You hold a PhD in Biological Sciences with at least 3-5 years of work experience in the pharmaceutical or diagnostic industry, alternatively you have a Scientific Master Degree with respectively 8-10 years work experience in histopathology laboratories
• Hands-on experience in histopathology and tissue analysis techniques is highly preferred
• You have experience in understating histopathology readouts and digital image formats and metadata
• You are experienced in vendor management as well as in contract management
• You are a good communicator and have strong persuasion and influencing capabilities to drive project needs and lead others in a matrix environment. This implies excellent English language skills.

Unwavering focus, collaborative teamwork and exceptional delivery are key behaviors that drive our mission of doing now what patients need next. Together, we can be transformative.

Your final Scientific Career Ladder (SCL)-Title will be evaluated according to your individual scientific experience.

Your application

Please upload your current resume and your latest certificates. The language of application is English.

We are looking forward to your application!

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Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche at Penzberg, near Munich, employs more than 7,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof. From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.