The in the Division of Genetics and Genomics at Boston Children’s Hospital, the Department of Pediatrics at Harvard Medical School, and the Programs in Metabolism and Medical and Population Genetics at the , is seeking exceptional candidates for postdoctoral fellowships focused on computational and statistical genetics methods development and/or next-generation sequencing and high-throughput genomic data analysis.The Flannick Lab develops computational approaches to use human genetic and broader genomic data to understand or better treat human diseases. Our work spans four intertwined themes: (i) rare coding-variant association studies; (ii) statistical models that integrate rare and common variants, gene annotations, and multi-omics data to quantify “genetic support” for candidate disease genes; (iii) disease subtyping and precision-medicine efforts that merge insights from rare and common diseases; and (iv) democratization of genetic findings through the development of large-scale knowledge portals that make complex results accessible to biologists and clinicians. We play leadership roles in international consortia including the Knowledge Portal Network (e.g., AMP-T2D and the Type 2 Diabetes Knowledge Portal), the Common Fund Data Ecosystem, and the NCATS Biomedical Translator. Projects meeting any level of ambition are available to motivated postdocs.The ideal candidate will be passionate about learning and developing cutting-edge techniques in the burgeoning field of “big data” genomic data science and be motivated to publish research that significantly impacts how genetics is used by biologists and pharmaceutical researchers to understand or treat human disease.RequirementsPhD in a quantitative fieldExperience with data analysis and programming/scripting; prior knowledge of computational biology or genetics is a plus but not required.The Flannick Lab has office space in both the Longwood Medical Area of Boston and the Kendall Square area of Cambridge, perhaps the most densely concentrated biomedical research communities in the world. Over 6,000 MDs or PhDs work as part of the Harvard Medical system in the Longwood Area alone, and the Broad Institute in Cambridge serves as a hub for the Harvard and MIT biomedical communities. These resources provide an unparalleled opportunity for a motivated postdoc to scientifically grow and achieve high impact science, set alongside all of the cultural and natural benefits of the broader Boston metropolitan area. Remote working options are also available.Interested individuals are encouraged to submit a cover letter, CV, list of publications, and brief statement of research interests when applying.
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