Sr. Research Associate, Pediatrics na UT Southwestern Medical Center

%3Cp%3E%3Cstrong%3EWHY UT SOUTHWESTERN?%3C/strong%3E%3Cbr%3EWith over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to %3Ca target=%22_blank%22 rel=%22noopener noreferrer%22 href=%22https://www.utsouthwestern.edu/newsroom/articles/year-2022/july-us-news-best-hospital.html%22%3EU.S. News %26amp; World Report%3C/a%3E, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you%27ll discover a culture of teamwork, professionalism, and a rewarding career!%26nbsp;%3Cbr%3E%3Cbr%3E%3Cstrong%3EJOB SUMMARY%3C/strong%3E%3Cbr%3EWorks under minimal direction to plan, coordinate, perform, and supervise performance of professional level medical or scientific research assignment related to particular or specialized field of endeavor.%26nbsp;%3Cbr%3E%3Cbr%3EWe are seeking a highly skilled research staff personnel member with expertise in murine models of liver disease, including neonatal handling, injection techniques, and tissue harvest. The ideal candidate will have experience in epithelial organoid culture from human liver tissues, immunofluorescence imaging, and co-culture assays to study epithelial-immune interactions, as well as familiarity with IACUC/IRB compliance and transcriptomic data interpretation.%3C/p%3E%3Cp%3EOther desired experience includes:%3C/p%3E%3Cul%3E%3Cli%3EProficiency in neonatal and adult mouse handling, injections (e.g., intraperitoneal, retro-orbital), and tissue harvest.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EExperience with murine models of biliary atresia, including rotavirus infection protocols, monitoring survival, and scoring disease severity.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EImmunofluorescence and confocal microscopy for liver and bile duct tissues.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EExpertise in isolating and expanding epithelial organoids from human liver and bile duct biopsies.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3ESkilled in 3D culture systems using basement membrane extracts (e.g., Matrigel, BME), and media optimization.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EHandling of organoids derived at both diagnosis and post-transplantation from pediatric patients.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EProliferation, viability, apoptosis, and differentiation assays.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3ECo-culture assays with immune cells to assess epithelial-immune interactions.%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EFamiliarity with transcriptomic data interpretation (e.g., from RNA-seq, scRNA-seq) is a plus.%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EUnderstanding of animal welfare regulations and human biospecimen research policies%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3Cli%3EExperience in preparing and updating IACUC and IRB protocols.%3C/li%3E%3C/ul%3E%3Cp%3E%3Cstrong%3EBENEFITS%3C/strong%3E%3Cbr%3EUT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:%3C/p%3E%3Cul%3E%3Cli%3EPPO medical plan, available day one at no cost for full-time employee-only coverage%3C/li%3E%3Cli%3E100% coverage for preventive healthcare-no copay%3C/li%3E%3Cli%3EPaid Time Off, available day one%3C/li%3E%3Cli%3ERetirement Programs through the Teacher Retirement System of Texas (TRS)%3C/li%3E%3Cli%3EPaid Parental Leave Benefit%3C/li%3E%3Cli%3EWellness programs%3C/li%3E%3Cli%3ETuition Reimbursement%3C/li%3E%3Cli%3EPublic Service Loan Forgiveness (PSLF) Qualified Employer%3C/li%3E%3Cli%3E%3Ca target=%22_blank%22 rel=%22noopener noreferrer%22 href=%22http://jobs.utsouthwestern.edu/benefits/#top%22%3ELearn more about these and other UTSW employee benefits!%3C/a%3E%3C/li%3E%3C/ul%3E%3Cp%3E%3Cbr%3E%3Cbr%3E%3Cstrong%3EEXPERIENCE AND EDUCATION%3C/strong%3E%3Cbr%3E%3Cstrong%3ERequired%3C/strong%3E%3C/p%3E%3Cul%3E%3Cli%3E%3Cstrong%3EEducation%3C/strong%3E%3Cbr%3EPhD with major coursework in field of assignment and no experience or%26nbsp;%3Cbr%3EMaster%27s Degree with major coursework in field of assignment or%26nbsp;%3Cbr%3EBachelor%27s Degree with major coursework in field of assignment or%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3C/ul%3E%3Cul%3E%3Cli%3E%3Cstrong%3EExperience%3C/strong%3E%3Cbr%3ENo experience required with PhD or%26nbsp;%3Cbr%3E5 years of laboratory experience with a Master%27s Degree including at least%26nbsp;%3Cbr%3E2 years at level of Research Associate or equivalent or%26nbsp;%3Cbr%3E6 years of laboratory experience with a Bachelor%27s Degree including at least%26nbsp;%3Cbr%3E2 years at level of Research Associate or equivalent%26nbsp;%3Cbr%3E%26nbsp;%3C/li%3E%3C/ul%3E%3Cp%3E%3Cbr%3E%3Cstrong%3EJOB DUTIES%3C/strong%3E%3C/p%3E%3Cul%3E%3Cli%3EOrganizes laboratory to which assigned; determines work assignments of subordinates, advising them as to techniques, procedures, and equipment to be utilized in solution of work problems; reviews completed work for professional quality and attainment of desired results.%3C/li%3E%3Cli%3ECompiles and evaluates research data, and develops new or revised techniques and procedures based upon such data.%3C/li%3E%3Cli%3EPerforms or supervises design, development, or adaptation of equipment or apparatus used in experiments or research to obtain desired results.%3C/li%3E%3Cli%3ECompiles and analyzes results of research assignments and submits to principal investigator.%3C/li%3E%3Cli%3EInstructs medical students, graduate students, residents, and other laboratory personnel of lower grade with respect to techniques, procedures, and equipment utilized in research or experiments.%3C/li%3E%3Cli%3EConfers with industrial, governmental, or other professional groups with respect to progress or results of research assignment.%3C/li%3E%3Cli%3EAssists principal investigator and other professional personnel in preparation of reports and papers for publication, usually exercising responsibility for writing of particular segment or phase of report or paper.%3C/li%3E%3Cli%3EPerforms other duties as assigned.%3C/li%3E%3C/ul%3E%3Cp%3E%3Cstrong%3ESECURITY AND EEO STATEMENT%3C/strong%3E%3Cbr%3E%3Cstrong%3ESecurity%3C/strong%3E%26nbsp;%3Cbr%3EThis position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 113.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.%3Cbr%3E%3Cbr%3E%3Cstrong%3EEEO Statement%3C/strong%3E%3Cbr%3EUT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.%3Cbr%3E%26nbsp;%3C/p%3E Candidatar-se agora