Hybrid Manager, Protein Sciences- Temporary 3 months presso Twist bioscience

Manager, Protein Sciences- Temporary 3 months

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive synthetic DNA technology that will change the world and enable widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, make everyday chemicals by using the atmosphere as the carbon source, enable plants to make their own fertilizers, and create in-vivo diagnostics that alert us when we are sick, and many more applications.

We are seeking an outstanding, innovative, and creative Sr. Scientist to join our antibody discovery effort. The Protein Sciences manager will play multiple roles within the HTIgG/Pharma group and will work with a team responsible for antibody and antigen production using mammalian cell expression systems.

What You’ll Be Doing

• Generating target over-expressing cell lines for antibody discovery work.
• Help manage antibody cloning, expression, and purification workflow in both high throughput and large-scale format.
• Help manage antibody QC and developability studies using CE-SDS, SDS-PAGE, HPLC, and nanoDSF-DLS. 
• Conduct antibody binding and functional assessment using ELISA and SPR. 
• Conduct antigen protein construct design, expression, and purification. 
• Plan, perform, analyze, and document laboratory experiments in support of antibody discovery
• Evaluate and support the implementation of new technologies
• Maintain laboratory instruments
• Work collaboratively under aggressive timelines

What You’ll Bring to the Team

• Strong background in antibody cloning, expression, and purification
• Strong Background in cell culture
• Successful candidates will be independent and creative researchers, capable of experimental design, execution, and troubleshooting.
• Your educational background includes a PhD/M.S. in immunology, cell biology, biochemistry, or a related discipline.
• Motivation to learn new scientific techniques and to work in a team environment is necessary.
• The ability to think outside the box is key
• Minimum of 3 years of management and relevant industry experience

Preferred Qualifications 

• Ph.D. or M.S. with industry experience required
• Postdoctoral experience preferred
• Experience expressing/purifying antibodies in HEK293/CHO and characterization using standard methods (SEC, CE-SDS, cIEF, MS) preferred
• A strong desire to work in a dynamic start-up environment is essential
• Ability to multitask and thrive in a fast-paced and challenging environment  
• Strong organization skills and proficiency in computer skills, including various databases
• Excellent oral/written communication and interpersonal skills a must
• Ability to multitask
• Excellent problem-solving capabilities
• Extraordinary attention to detail and planning
• Outstanding oral and written communication skills
• Proficiency with Microsoft Word, Excel, and PowerPoint

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.