Associate Scientist I, Clinical Serology, Nonclinical & Immunoassay na Vaxcyte
Vaxcyte · San Carlos, Estados Unidos Da América · Onsite
- Junior
- Escritório em San Carlos
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Summary:
Vaxcyte is looking for an energetic and talented Associate Scientist I to manufacture and test all reagents required for immunoassay detection of multi-valent vaccines. In particular, the reagents we are using need to be conjugated to different entities and then characterized and catalogued for our multiplexed assays. Extreme control of this assay is required to maintain DS shelf life and more importantly, ensuring DP compounding is successful in relation to the final dose of each DS in the clinic.
We require an Associate Scientist I who will continue the development and optimization of assay suites for our current 3 programs, and for upcoming research projects. This person will be part of a larger team that will continue this development. The role requires an extremely high level of organization, and the ability to maintain large volumes of data for the various DS and DP entities. In addition, the successful candidate will require significant experience in developing, trouble shooting and running ELISA-type assays, including generation of the critical reagents, which includes generating high-affinity antibodies specific to the antigen.
Essential Functions:
- Help continue the development and optimization of assay suites for our current 3 programs, and for the following research projects.
- Have an extremely high level of organization, and the ability to maintain large volumes of data for the various DS and DP entities.
- Demonstrate experience in developing, trouble shooting and running ELISA-type assays, including generation of the critical reagents, which includes generating high-affinity antibodies specific to the antigen.
Requirements:
- BSc 0-2 years in Molecular Biology, Chemistry, Analytical Chemistry, Organic Biochemistry considered.
- Ideal candidate will have a significant background in plate-based assay development and antibody characterization including HPLC and Octet.
- Experience in protein analysis such as SEC, HPLC, SDS-page, CE-SDS, and cIEF and binding kinetics is a plus.
- Having a high degree of organizational capabilities for both reagents and experimental scheduling a must.
- Prior experience of transferring methods to external partners for validation and GMP activities will be of a significant benefit, and first-hand experience of a QC environment would also be advantageous.
- Experience in immunoassay development, qualification, validation, trouble shooting and aiding in OOS investigations is highly desired.
- The ability to present complex data sets and independently propose and design follow-up experiments are also required.
- Maintaining good laboratory practices, safety and record keeping for them-selves and their team is required.
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.
